Treatment with metformin glycinate reduces SARS-CoV-2 viral load: An in vitro model and randomized, double-blind, Phase IIb clinical trial메트포르민 글리시네이트로 치료하면 SARS-CoV-2 바이러스 부하 감소: 시험관 내 모델 및 무작위, 이중 맹검, IIb상 임상 시험Randomized Controlled Trial Published on 2022-08-012022-09-11 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] adaptive aligned Alpha caused Cell Clinical data clinical trial conducted control group coronavirus disease COVID-19 COVID-19 patients COVID-19 treatment dose doses double-blind drug effort Epsilon evaluate exposure to Health Health crisis highlight highlighting identify IIb in vitro in vitro model in vitro result in vitro study in vivo increased survival indicate inhibit metformin Metformin glycinate New coronavirus new coronavirus SARS-CoV-2 new treatment strategy new virus oxygen phase Randomized reduce reduced SARS-CoV-2 SARS-CoV-2 variants SARS-CoV-2 viral SARS-CoV-2 viral load SARS-CoV-2 viral load. severe disease supplementary oxygen tested the SARS-CoV-2 therapeutic option treated Treatment Treatment effectiveness triggered variant variants of interest Vero E6 VERO E6 cells viral infection Viral load viral replication [DOI] 10.1016/j.biopha.2022.113223 PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 convalescent plasma코로나19 회복기 혈장Article Published on 2022-07-212022-09-11 Journal: Blood [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody antibody-dependent cellular cytotoxicity benefit CCP collected complement Complement activation convalescent plasma coronavirus coronavirus disease COVID-19 disease early disease Efficacy function Health Health crisis high-titer CCP Hospitalized Immunosuppressed immunosuppressed patient immunosuppressed patients indications location moderate moderate to severe Outpatient pandemic phagocytosis plasma prophylactic therapy provide provided randomized trial respiratory safety profile SARS-CoV-2 SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus severe disease symptom onset the patient The United States therapeutic potential Therapies transfused Treatment Trial United States Viral viral neutralization with COVID-19 [DOI] 10.1182/blood.2021012248 PMC 바로가기 [Article Type] Article
Depressive symptoms among adults in 2018-2019 and during the 2020 COVID-19 pandemic in Italy2018-2019년과 이탈리아의 2020년 COVID-19 범유행 기간 동안 성인의 우울 증상Article Published on 2022-07-152022-09-11 Journal: Journal of affective disorders [Category] COVID19(2023년), SARS, 치료기술, [키워드] 2020 COVID-19 pandemic 95% CI Administered average coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic declined Depression depressive depressive symptom Depressive symptoms detect Effect expected Factor framework Health Health crisis higher education increasingly individual Italian Italy longitudinal Longitudinal evaluation mental health Nationally representative study pandemic PHQ-2 Post-lockdown. Prevalence produced Resilience restriction returned risk significantly higher South Symptom System were assessed while women [DOI] 10.1016/j.jad.2022.04.131 PMC 바로가기 [Article Type] Article
Detection of COVID-19 from CT and Chest X-ray Images Using Deep Learning Models딥 러닝 모델을 사용하여 CT 및 흉부 X선 이미지에서 COVID-19 감지Review Published on 2022-07-012022-09-11 Journal: Annals of biomedical engineering [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Anomaly approach approaches artificial intelligence automatic detection cause caused chest X-ray Chest X-ray images Convolutional neural network coronavirus COVID COVID-19 CT deep deep learning deep learning. detection detection system diagnose Early detection estimate experiment Health Health crisis health system health systems help Image IMPROVE learning Model offer outbreak pathogenic virus pathology problem problems Radiographic researcher respiratory syndrome coronavirus respiratory syndrome coronavirus 2 SARS-CoV-2 severe respiratory syndrome Spread tomographic image Wuhan Wuhan, China X-ray [DOI] 10.1007/s10439-022-02958-5 PMC 바로가기 [Article Type] Review
Sensitive and specific clinically diagnosis of SARS-CoV-2 employing a novel biosensor based on boron nitride quantum dots/flower-like gold nanostructures signal amplification질화붕소 양자점/꽃모양 금 나노구조 신호 증폭 기반의 새로운 바이오센서를 이용한 SARS-CoV-2의 민감하고 구체적인 임상 진단Article Published on 2022-07-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification biosensor Boron boron nitride carbon characteristic clinical sample clinical samples clinical trials clinically comparable COVID-19 COVID-19 outbreak COVID-19 pandemic cross-reactivity cutoff value Detection limit Diagnosis diagnosis of SARS-CoV-2 DNA Effect electrochemical biosensor evaluate form gold group growth Health Health crisis IAV Influenza influenza A Mutation nucleic acid nucleic acid amplification Patient platform point-of-care positive quantitation Quantitative receiver operating characteristic receiver operating characteristic curve remained RNA RNA fragment RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Screen sensitive sensitivity significant difference specificity ssDNA statistical analysis t-test Virus diagnosis. was tested [DOI] 10.1016/j.bios.2022.114209 PMC 바로가기 [Article Type] Article
Is the COVID-19 pandemic impacting on the risk of African Swine Fever virus (ASFV) introduction into the United States? A short-term assessment of the risk factorsCOVID-19 대유행이 아프리카돼지열병 바이러스(ASFV)가 미국으로 유입될 위험에 영향을 미치고 있습니까? 위험 요인에 대한 단기 평가Article Published on 2022-07-012022-09-11 Journal: Transboundary and emerging diseases [Category] 치료기술, [키워드] 95%CI activities activity affected African African Swine Fever Virus analysis China connection Consequences contagious contagious disease country COVID-19 COVID-19 pandemic disease driver Fever Flow global connections global public health Health crisis high mortality highlight highlighting identify International majority outbreak P-value pathway Pathways populations Prevent public health recognizing response Result risk risk factor Spread spread to the United State transboundary disease. United States virus was used zoonosis [DOI] 10.1111/tbed.14330 PMC 바로가기 [Article Type] Article
Understanding How and by Whom COVID-19 Misinformation is Spread on Social Media: Coding and Network AnalysesCOVID-19 잘못된 정보가 소셜 미디어에서 어떻게 그리고 누구에 의해 전파되는지 이해하기: 코딩 및 네트워크 분석Article Published on 2022-06-202022-09-11 Journal: Journal of Medical Internet Research [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed Characteristics characterized collected COVID-19 COVID-19 pandemic data set dissemination distribution emotion Epidemic exhibited feature FIVE global health crisis Government Health Health crisis health misinformation help highest include infodemiology information International likelihood media medical information misinformation misinformation spread network occurred pandemic producing Radiation social media Spread theoretical model. understanding width with COVID-19 [DOI] 10.2196/37623 PMC 바로가기 [Article Type] Article
Clinical and Genetic Characteristics of Coronaviruses with Particular Emphasis on SARS-CoV-2 VirusSARS-CoV-2 바이러스에 특히 중점을 둔 코로나바이러스의 임상 및 유전적 특성Review Published on 2022-06-192022-09-11 Journal: Polish journal of microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] caused clinical clinical courses coronavirus disease Coronavirus disease 2019 Course courses COVID-19 Culture diagnostics effort epidemiological situation Genetic genetic determinant genetic determinants Health Health crisis Infection knowledge mechanism pandemic Particular prevention of COVID-19 Research SARS-CoV-2 severity Society susceptibility the disease Treatment Vaccine vaccine. virus transmission [DOI] 10.33073/pjm-2022-022 PMC 바로가기 [Article Type] Review
Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics치료제로서의 최적 기능을 위한 Anti-SARS-CoV-2 단일클론항체 변형 전략 평가Article Published on 2022-06-032022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alleviate antibody Antibody-dependent enhancement caused Cell circulating closure Combination coronavirus country COVID-19 infection COVID-19 infections COVID-19 pandemic death disease Economy Effect epitope Epitopes Health crisis Human human population humoral immune response in vitro infecting investigated LALA lockdown mAb mAbs modify monoclonal antibodies monoclonal antibody Mutation neutralize produced public health crisis public health measure public health measures reduce reported respiratory resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 SARS-CoV2 spike protein serum severe acute respiratory syndrome Coronavirus Spike protein Spread the antibody the disease the spike protein therapeutic option therapy These data Viral viral variant virus writing [DOI] 10.1371/journal.pone.0267796 PMC 바로가기 [Article Type] Article
Are effects of COVID-19 pandemic on financial markets permanent or temporary? Evidence from gold, oil and stock marketsResearch article Published on 2022-06-012022-10-05 Journal: Resources Policy [Category] 진단, [키워드] Baker COVID-19 case COVID-19 cases COVID-19 pandemic Davis determine domain Effect Financial markets Frequency Health crisis IDEMV index Islamic stock markets Jone Other Research time variable variables volatility [DOI] 10.1016/j.resourpol.2022.102637 [Article Type] Research article